Results of nonstationary fluctuation analysis of IHC ΔCm
| Csv(aF) ± SEM | Capp, weight(aF) [95% CI] | μweight [95% CI] | Capp(aF) [95% CI] | μ [95% CI] | Trend corr. | |
|---|---|---|---|---|---|---|
| Mature, K+ (n = 15) | 45 ± 1 (n = 574) | 95 [55, 141] | 1.6 [1.1, 2.1] | 94 [28, 159] | 1.6 [0.8, 2.3] | 1 |
| 102 [58, 149] | 1.6 [1.1, 2.2] | 98 [25, 174] | 1.6 [0.8, 2.4] | 2 | ||
| Mature K+, ryanodine, (n = 4) | 145 [72, 221] | 2.1 [1.3, 3.0] | 160 [72, 251] | 2.3 [1.3, 3.3] | 1 | |
| Immature K+ (n = 14) | 48 ± 1 (n = 602) | 147 [96, 200] | 2.0 [1.5, 2.6] | 155 [87, 223] | 2.1 [1.4, 2.8] | 1 |
| 166 [117, 223] | 2.2 [1.7, 2.8] | 170 [110, 240] | 2.3 [1.7, 3.0] | 2 | ||
| Immature Cs+ (n = 6) | 133 [63, 208] | 1.9 [1.2, 2.7] | 132 [41, 232] | 1.9 [1, 2.9] | 1 |
Summary of the results obtained with and without weighting as well as with the two different trend corrections. Trend correction 1 corresponds to subtraction of a trend function obtained by low-pass filtering of the data, and correction 2 used subtraction of a double-exponential fit. The average number of synaptic vesicles involved in a fusion event (μ), was calculated according to μ = (Capp/Csv + 1)/2. corr., Correction.