Effect of chronic fluoxetine and environmental enrichment on forebrain neocortical gene expression in SFR and IMS micea
| Gαq | egr-3 | GABAA α1 | |
|---|---|---|---|
| SFR-F(P60) | 0.87 ± 0.16 | 0.57 ± 0.12 | 0.74 ± 0.12 |
| SFR-F(P28) | 1.35 ± 0.21 | 2.24 ± 0.43*** | 1.20 ± 0.16 |
| SFR-E | 1.26 ± 0.16 | 1.08 ± 0.15 | 1.54 ± 0.07** |
| IMS | 2.43 ± 0.42*** | 0.82 ± 0.29 | 1.11 ± 0.31 |
| IMS-F(P60) | 0.38 ± 0.12* | 0.55 ± 0.13 | 0.96 ± 0.14 |
| IMS-F(P28) | 0.24 ± 0.07** | 0.22 ± 0.06** | 0.53 ± 0.07** |
| IMS-E | 1.34 ± 0.17 | 0.67 ± 0.25 | 0.91 ± 0.21 |
↵aData are expressed as fold-change relative to SFR controls and represent mean ± SEM of determinations made from five to eight animals per group. ***p < 0.001; **p < 0.01; *p < 0.05 (ANOVA; post hoc Tukey–Kramer multiple comparisons).