Axon guidance defects and overextension phenotypes in mutant strains
| Genotype | Ventral guidance AVM axon (% defective) | Overextension PLM axon (%) | Overextension to AVM PLM axon (%) | n |
|---|---|---|---|---|
| glo-4(ok623) | 0 | 23 | 3 | 131 |
| glo-1(zu391) | 0 | 21 | 3 | 194 |
| fsn-1(hp1) | 0 | 28 | 5 | 257 |
| rpm-1(ur299) | 0 | 90 | 15 | 270 |
| rpm-1(ur299);glo-4(ok623) | 0 | 100 | 42* | 119 |
| rpm-1(ur299);glo-1(zu391) | 0 | 100 | 87** | 146 |
| rpm-1(ur299);fsn-1(hp1) | 0 | 100 | 93** | 213 |
| slt-1(eh15) | 32 | 0 | 0 | 238 |
| slt-1(eh15);glo-4(ok623) | 63* | 7 | 0 | 208 |
| slt-1(eh15);fsn-1(hp1) | 34 | 28 | 2 | 181 |
Strains were analyzed in the zdIs5(mec-4::GFP) background at 20° C. n, Total number of animals scored. Asterisks indicate differences between rpm-1 or slt-1 single- or double-mutant strains determined by a two-tailed Z test (*p < 0.005; **p < 0.0005).