Regions | Class | Normalized betweenness,bi | Degree,ki |
---|---|---|---|
Right lateral fronto-orbital gyrus | Paralimbic | 3.39 | 13 |
Right cingulate region | Paralimbic | 3.00 | 18 |
Left lingual gyrus | Association | 2.87 | 13 |
Left lateral occipitotemporal gyrus | Association | 2.33 | 8 |
Right lingual gyrus | Association | 2.31 | 10 |
Left middle temporal gyrus | Association | 2.25 | 5 |
Right superior occipital gyrus | Association | 2.06 | 9 |
Left medial fronto-orbital gyrus | Paralimbic | 1.94 | 5 |
Right medial fronto-orbital gyrus | Paralimbic | 1.91 | 12 |
Left superior temporal gyrus | Association | 1.81 | 7 |
Left uncus | Paralimbic | 1.81 | 7 |
Left supramarginal gyrus | Association | 1.57 | 6 |
Left inferior frontal gyrus | Association | 1.55 | 9 |
Right middle frontal gyrus | Association | 1.52 | 12 |
The hub regions (bi> 1.5) in the structural cortical network of the AD group were listed in a descending order of their normalized betweenness, bi. The regions were classified as primary, association, and paralimibic as described by Mesulam (1998). ki denotes the degree of region i. For statistical properties of all regions included in the cortical network, see supplemental Table 3 (available at www.jneurosci.org as supplemental material).