Table 1.

Talairach coordinates of regions extracted from the CS+ > CS− in early acquisition contrast (false discovery rate <0.05) and their differential responding in subsequent stages

Region	Side	CS+ > CS−^a			Coordinates x, y, z	Volume (mm³)
Region	Side	Late acquisition	Early reversal	Late reversal	Coordinates x, y, z	Volume (mm³)
Caudate	L	^**	NS	^***	−10, 3, 8	210
Caudate	R	^***	NS	^**	12, 4, 9	124
Putamen	L	^***	NS	NS	−26, −3, 7	283
Putamen	R	NS	NS	NS	24, 3, −2	291
Insula	L	^***	NS	^**	−44, 6, 6	3825
Insula	R	^***	NS	^***	45, 7, 5	3366
Thalamus	R	^***	NS	^*	9, −12, 3	310
Thalamus	R	^*	NS	^**	5, −13, 14	274
Midbrain	L	^*	NS	^**	−7, −12, −7	74
Midbrain	L	NS	NS	NS	−7, −23, −10	119
dACC	M	^***	NS	^***	2, 4, 40 (BA32)	1756
SFG	M	^***	NS	^***	0, −8, 59 (BA6)	2782
Precuneus	L	NS	NS	NS	−10, −40, 43 (BA7)	835
Precuneus	R	NS	NS	NS	4, −57, 48 (BA7)	450
Cerebellum	R	NS	NS	NS	14, −42, −15	185

↵^aTwo-way t test conducted on the percent BOLD signal change to CS+ versus CS− in each phase. BA, Brodmann area; dACC, dorsal anterior cingulate cortex; SFG, superior frontal gyrus.
↵*p < 0.05; **p < 0.01; ***p < 0.001, significantly stronger responses to CS+ compared to CS− in late acquisition, and new CS+ compared to new CS− during reversal.