Main unitary conductance of recombinant and native Kv4 channels
| Kv4 channel | γm (pS) | n |
|---|---|---|
| Kv4.2 | 4.1 ± 0.3 | 3 |
| Kv4.3 | 4.4 ± 0.3 | 5 |
| Kv4.2:DPP6-S | 7.7 ± 0.3 | 3 |
| Kv4.3:DPP6-S | 6.9 ± 0.3 | 5 |
| Kv4.2 ternary | 7.8 ± 0.4 | 3 |
| CGN, rat | 7.3 ± 0.4 | 3 |
| CGN, mouse | 7.4, 7.8 | 2 |
| CGN, dpp6−/− | 4.2 ± 0.3 | 3 |
| Kv4.2:DPP6-S (D18N, E20Q) | 4.8 ± 0.2 | 3 |
| Kv4.3:DPP6-S (D18N, E20Q) | 4.9 ± 0.1 | 4 |
All values are means ± SEM from n cell-attached patches (third column). For CGN (mouse), two independent estimates are shown. The γm values were determined from the slope conductances of the unitary current–voltage relations corresponding to the L3 level in each condition (Figs. 2, 4). The γm of the Kv4.2 channel was significantly different from those of Kv4.2+DPP6-S and CGN (rat) channels at p < 0.001 (one-way ANOVA).