Postsynaptic cell type-dependent properties of MF–EPSCs
| Amplitude of successes during the 5 AP trains (pA)a | Transmission probability during 5 AP trains (%)b | euEPSC during 5 AP trains (pA)c | Transmission probabilityfor the first AP (%)d | euEPSC for the first AP (pA) | τ decay of EPSCs duringthe 5 AP trains (ms) | |
|---|---|---|---|---|---|---|
| IvyC | 92.5 ± 24.2 | 64.4 ± 16.7 | 72.5 ± 29 | 55.3 ± 14.1 | 63.5 ± 32.5 | 1.74 ± 0.29 |
| RSBC | 73.6 ± 19.4 | 57.8 ± 9.3 | 49.4 ± 13.1 | 43.4 ± 20.7 | 58.6 ± 29.9 | 2.32 ± 0.58 |
| FSBC | 28 ± 4.4 | 21.6 ± 6.6 | 7.2 ± 2 | 22.9 ± 5.2 | 12.7 ± 3.4 | 2.12 ± 0.36 |
| SLC 1–5 AP (46–50 AP) | N/A (49.9 ± 9.3) | 5.3 ± 1.1 (34.6 ± 3.3) | 3 ± 0.8 (21.5 ± 5.7) | 2.4 ± 0.8 | 1.7 ± 0.3 | N/A (3.54 ± 0.53) |
N/A, Not applicable.
↵aAmplitude of successes during the first five presynaptic action potentials (APs), excluding failures (significant differences: FSBCs and RSBCs: p = 0.037, FSBCs and IvyCs: p = 0.012; Mann–Whitney nonparametric U test).
↵bTransmission probability during 5 AP trains: Percentage of trials when the first five presynaptic action potentials at 50 Hz were followed by monosynaptic MF–EPSCs (significant differences: FSBCs and RSBCs: p = 0.037, RSBCs and SLCs: p = 0.01, and IvyCs and SLCs: p = 0.0016; Mann–Whitney test).
↵ceuEPSC amplitudes included both successes and failures (significant differences: for the 1st AP, FSBCs and RSBCs: p = 0.037, FSBCs and IvyCs: p = 0.037, FSBCs and SLCs: p = 0.012, RSBCs and SLCs: p = 0.014, and IvyCs and SLCs: p = 0.0027; during the 5 AP train, FSBCs and RSBCs: p = 0.037, FSBCs and IvyCs: p = 0.022, RSBCs and SLCs: p = 0.012, and IvyCs and SLCs: p = 0.0019; Mann–Whitney test). N (number of cells) = 5, 3, 5, and 15 for IvyCs, RSBCs, FSBCs, and SLCs, respectively.
↵dTransmission probability for the first AP: Percentage of trials when the first presynaptic action potential was followed by monosynaptic MF–EPSCs (significant differences: FSBCs and SLCs: p = 0.013, RSBCs and SLCs: p = 0.006, and IvyCs and SLCs: p = 0.0009; Mann–Whitney test).