4 h saline | 4 h pilo | 10 d saline | 10 d pilo | 31 d saline | 31 d pilo | |
---|---|---|---|---|---|---|
Holding potential (mV) | −70.9 ± 1.4 (7) | −69.3 ± 0.5 (9) | −68.1 ± 0.9 (8) | −71.8 ± 1.4 (8) | −68.7 ± 0.8 (12) | −66.9 ± 0.7 (15) |
Resistance (MΩ) | 150.4 ± 21.7 (7) | 188.4 ± 24.1 (9) | 173.2 ± 20.3 (8) | 141.2 ± 17.0 (8) | 247.2 ± 22.6 (12) | 216.0 ± 12.9 (15) |
Capacitance (pF) | 71.2 ± 5.6 (7) | 74.7 ± 4.7 (9) | 71.3 ± 3.7 (8) | 109.7 ± 13.0 (8)** | 68.5 ± 3.8 (12) | 67.6 ± 3.6 (15) |
Maximum current (pA) | 672.7 ± 90.5 (7) | 682.0 ± 73.5 (9) | 659.5 ± 83.4 (8) | 939.2 ± 85.5 (8)* | 591.0 ± 36.5 (12) | 905.3 ± 48.8 (15)*** |
Current density (pA/pF) | 9.4 ± 0.9 (7) | 9.3 ± 1.0 (9) | 9.4 ± 1.3 (8) | 9.3 ± 1.4 (8) | 9.6 ± 0.6 (12) | 13.7 ± 1.0 (15)*** |
Activation V50 (mV) | −77.4 ± 1.8 (6) | −76.2 ± 1.9 (6) | −74.9 ± 1.4 (8) | −81.7 ± 1.9 (6)* | −75.8 ± 1.8 (8) | −74.8 ± 1.1 (8) |
Inactivation V50 (mV) | −88.3 ± 1.8 (7) | −85.3 ± 1.2 (9) | −85.8 ± 1.2 (8) | −90.8 ± 1.5 (8)* | −86.7 ± 1.4 (12) | −80.4 ± 0.6 (15)*** |
Decay constant (ms) | 12.4 ± 0.8 (7) | 12.7 ± 0.5 (9) | 12.5 ± 1.2 (8) | 16.6 ± 0.8 (8)* | 12.2 ± 0.5 (12) | 13.9 ± 0.4 (15)* |
Maximum charge (pC) | 12.4 ± 1.1 (7) | 12.6 ± 1.1 (9) | 12.8 ± 2.0 (8) | 21.8 ± 1.5 (8)** | 11.6 ± 1.0 (12) | 15.8 ± 0.9 (15)** |
Charge density (pC/pF) | 0.22 ± 0.02 (7) | 0.21 ± 0.03 (9) | 0.18 ± 0.01 (8) | 0.20 ± 0.01 (8) | 0.19 ± 0.02 (12) | 0.25 ± 0.01(15)* |
↵*p < 0.05, **p < 0.01, ***p < 0.001; unpaired t test. n values are given in parentheses.