Relative presence of neuron types that are affected in Arx(GCG)10+7 mutants (WT, 100%)
| Cortical layers I–IV | Cortical layers V–VI | All cortical layers | Hippocampus | Striatum | |
|---|---|---|---|---|---|
| ARX+ | 68 ± 5* | 53 ± 13* | 58 ± 9* | 69 ± 15* | 49 ± 7* |
| CB28K+ | 64 ± 9** | 77 ± 14 | 67 ± 9** | 56 ± 16 | 47 ± 6*** |
| NPY+ | 100 ± 5 | 100 ± 11 | 100 ± 7 | 100 ± 19 | 69 ± 8** |
| ChAT+ | — | — | — | — | 39 ± 16*** |
The unit of measure is percentage of immunostained cells present in defined areas in brain sections of bregma 1.0 and 0.5, relative to WT values that were set at 100%. CB28K, Calbindin 28K; —, absence of ChAT + cells. Values are average ± SEM.
↵*p < 0.05, **p < 0.01, ***p < 0.001 versus wild type.