Table 1.

Parameters of the unified conceptual model to produce three classes of duration tuning

Onset EPSPOffset EPSPOnset IPSPConceptual model
    Supra-; low; transientNoneSustainedAnti-coincidence
    Supra-; low; transientSub-; low; transientSustainedCoincidence
    Supra-; high; transientNoneSustainedAnti-coincidence
    Supra-; high; transientSub-; high; transientSustainedCoincidence
    Supra-; low/high; sustainedNoneSustained; adaptingAnti-coincidence
    Supra-; low/high; sustained; augmentingNoneSustainedAlternative anti-coincidence
  • Supra-, Suprathreshold synaptic input to the DTN; sub-, subthreshold input to the DTN (i.e., requires coincidence with an additional excitatory event); low, low spiking threshold (i.e., neurons providing this input spike with low stimulus input energy); high, high spiking threshold spiking (i.e., neurons providing this input spike only with high stimulus input energy); transient, duration of the synaptic input is transient; sustained, synaptic input lasting as long or longer than the stimulus; augmenting, input strengthens over time; adapting, input weakens (adapts) over time.