Table 5.

Covariation between the main pain processing-related areas modulated by attention (aIC) or emotion (ACC) and potential pain modulators

Region (BA)ConditionMNI coordinates (x, y, z)t scoreCluster size
Attentional condition (areas that covary with aIC)
    aICAH−28, 16, 65.6235336
    SPP (BA7)AH−18, −50, 704.333224
    ERC (BA28)AH16, −4, −382.76140
Emotional condition (areas that covary with ACC)
    ACC (BA24)BO−2, 10, 323.7744672*
BO4, −2, 325.9814672*
Inferior frontal—triangular part (BA45/47)BO46, 32, 104.158752*
Inferior frontal—orbital part (BA47)BO48, 30, −43.706752*
PAGBO6, −32, −163.184480
  • Cluster size refers to the size of the cluster in cubed millimeters with t values superior to 2.5. t scores and cluster sizes significant in the directed search are indicated in bold. t scores significant in global search are bolded and underlined.

  • *Same cluster with more than one peak.