Arrestin competition model can capture the changes in response area
| Strain | Area/AreaWT,experiment | Area/AreaWT, model |
|---|---|---|
| GRK1 +/− (n = 43) | 1.95 ± 0.08 | 2.02 |
| GRK1 +/− Arr1 +/− (n = 39) | 1.30 ± 0.07 | 1.34 |
| Arr1 +/− (n = 36) | 0.68 ± 0.06 | 0.74 |
Minimizing the mean-square error between experimental values (middle column) and predicted values (right column) yielded β0/α = 6 and γ0/σ = 8. Experimental data are from dim flash responses.