Quantitative parameters of the plateau potential at different postnatal periods
| Parameter (mEC LIII) | 1 mm [Ca2+]o | ||||
|---|---|---|---|---|---|
| P5–P7(n = 10) | Versus | P8–P10(n = 6) | Versus | P11–P13( n = 5) | |
| Plateau duration (s) | 4.8 ± 1.8 | * | 2.8 ± 1.7 | ns | 2.7 ± 0.7 |
| Plateau amplitude (mV) | 9.2 ± 2.3 | ns | 11.6 ± 3.7 | ns | 11.3 ± 2.5 |
| Spike frequency withinplateau (Hz) | 4.4 ± 1.3 | ** | 14.8 ± 10.6 | ns | 11.5 ± 0.6 |
| Number of spikes withinplateau | 21 ± 11 | ns | 32 ± 17 | ns | 31 ± 6 |
| AHP amplitude (mV) | 3.2 ± 0.9 | ns | 3.4 ± 1.4 | ns | 4 ± 1.3 |
| AHP duration (s) | 12.6 ± 8.5 | ns | 6.5 ± 2.4 | ns | 7 ± 4.6 |
| Recording membranepotential (mV) | −63.5 ± 3.2 | ns | −63.1 ± 2.6 | ns | −62.8 ± 1.3 |
Averaged data are given as mean± SD. The plateau potential was induced by depolarizing current steps (5–10 pA, 0.2–1 s). Recordings were made in ACSF containing 1 mm Ca2+. iGluRs and GABAARs were blocked as detailed in Materials and Methods. Unpaired two-tailed t test or Mann-Whitney rank sum test (versus, i.e., left versus right) values are indicated as follows:
↵*p < 0.05,
↵**p < 0.01. ns, Not significant.