Stereological estimates of total cerebellar Purkinje cells (values are in thousands)
| Animal | WT | SCA1-L15 | SCA1-FBR | SCA1-NPC |
|---|---|---|---|---|
| Purkinje cell layer | ||||
| #1 | 207.28 (0.05) | 72.61 (0.08) | 73.54 (0.09) | 159.82 (0.07) |
| #2 | 149.11 (0.07) | 69.48 (0.09) | 97.22 (0.1) | 138.80 (0.05) |
| #3 | 189.98 (0.05) | 74.09 (0.14) | 85.43 (0.09) | 98.84 (0.09) |
| #4 | 138.22 (0.07) | 92.25 (0.08) | 74.31 (0.07) | 93.85 (0.07) |
| #5 | 215.55 (0.06) | 83.97 (0.08) | 122.62 (0.07) | |
| #6 | 221.52 (0.05) | |||
| Mean N (CE)a | 186.94 (0.06) | 78.48 (0.09) | 82.63 (0.09) | 122.79 (0.07) |
| CVb | 0.19 | 0.12 | 0.13 | 0.22 |
| Granule cell and molecular layer | ||||
| #1 | 1.44 (0.81) | 36.55 (0.1) | 19.76 (0.17) | 23.55 (0.22) |
| #2 | 2.41 (0.51) | 15.93 (0.21) | 26.83 (0.15) | 11.34 (0.27) |
| #3 | 0.9 (l) | 34.76 (0.14) | 31.19 (0.14) | 13.69 (0.18) |
| #4 | 7.69 (0.3) | 20.37 (0.2) | 23.50 (0.13) | 14.63 (0.19) |
| #5 | 0.97 (1) | 24.69 (0.18) | 25.42 (0.14) | |
| #6 | 0.74 (l) | |||
| Mean N (CE)a | 2.36 (0.77) | 26.46 (0.16) | 25.33 (0.15) | 17.73 (0.2) |
| CVb | 1.13 | 0.34 | 0.19 | 0.36 |