Table 1.

Intensity discrimination-related and intensity memory-related activations and deactivations for pain

RegionDiscriminationMemory
Activation
    VMPFC
        Right(−)3.57 (7522, 24, 44, −16)
        Left(−)4.03 (7522, −14, 38, −16)
    Thalamus
        Right3.18 (853, 10, −12, −2)(−)
        Left3.19 (853, −10, −12, 4)(−)
    Caudate n.(dorsal)(ventral)
        Right3.75 (853, 10, 12, 8)4.12 (7522, 20, 22, −2)
        Left4.3 (504, −16, 16, 8)3.43 (7522, −12, 20, −2)
    Anterior insula
        Right4.3 (853, 32, 22, 4)(−)
        Left4.93 (1184, −32, 18, −4)(−)
    Frontal pole (BA10)
        Right(−)(−)
        Left4.35 (1184, −34, 62, 2)4.43 (7522, −32, 48, 18)
    DLPFC (BA9)
        Right4.9 (589, 40, 36, 26)(−)
        Left4.98 (791, −40, 26, 28)3.51 (7522, −46, 28, 28)
    ACC
        Right4.62 (2270, 6, 12, 42)(−)
        Left4.88 (2270, −8, 12, 46)3.35 (580, −4, 18, 42)
    Left M1/SI/PMA4.33 (782, −52, −38, 50)4.69 (7522, −56, −16, 40)
    PPC-IPL
        Right(−)(−)
        Left3.12 (782, −38, −50, 40)4.83 (7522, −44, −28, 54)
    PPC-SPL
        Right(−)(−)
        Left(−)(−)
    DFC (BA8)
        Right(−)3.59 (1335, 56, −14, 36)
        Left3.60 (−32, −12, 52)3.88 (580, −20, 6, 58)
    Right SI (leg)(−)3.26 (1335, 10, −40, 72)
    SII(−)(−)
Deactivation
        Right SI−3.28 (530, 10, −44, 68)(−)
        Left SI(−)−3.08 (5056, −4, −44, 70)
        Right BA19−4.73 (1396, 52, −70, −12)(−)
        Left PCC−4.18 (583, −8, −64, 14)−4.5 (5056, −6, −64, 30)
        Right thalamus(−)−4.23 (5056, 18, −26, 12)
        Left thalamus(−)−4.04 (5056, −18, −22, 12)
  • Peak Z-scores were obtained from group analysis. Cluster sizes and peak locations within significant clusters are listed within the parentheses as number of voxels and x, y, z coordinates according to standard stereotaxic space. Note that a single statistically significant cluster can extend across multiple anatomic regions and have multiple local maxima. Caudate n., Caudate nucleus.