Table 4.

Loss of dorsal CST axons in the lumbar spinal cords of MOG peptide EAE mice is bilaterally symmetric

Days post-MOG peptideTreatmentAxon countr2
RightLeft
NormalUntreated28232945
35CFA 131163010
101CFA 128303069
101CFA 229373120
0.997
35MOG peptide 119822329
35MOG peptide 218041955
35MOG peptide 318191489
35MOG peptide 415931937
35MOG peptide 5702979
35MOG peptide 617761659
0.974
101MOG peptide 7275307
101MOG peptide 8247215
101MOG peptide 9397536
101MOG peptide 1018701335
0.956
  • EYFP+ axons were counted in the right and left dorsal corticospinal tracts in L3 spinal cord cross-sections from normal, CFA control, and MOG peptide EAE EmxCre/RosaSTOP-EYFP mice. The regression coefficient r2 was close to 1 in each group, indicating little variance between the axon counts on the right and left side in either the control or MOG peptide EAE mice (Snedecor and Cochran, 1989).