Days post-MOG peptide | Treatment | Axon count | r2 | |
---|---|---|---|---|
Right | Left | |||
Normal | Untreated | 2823 | 2945 | |
35 | CFA 1 | 3116 | 3010 | |
101 | CFA 1 | 2830 | 3069 | |
101 | CFA 2 | 2937 | 3120 | |
0.997 | ||||
35 | MOG peptide 1 | 1982 | 2329 | |
35 | MOG peptide 2 | 1804 | 1955 | |
35 | MOG peptide 3 | 1819 | 1489 | |
35 | MOG peptide 4 | 1593 | 1937 | |
35 | MOG peptide 5 | 702 | 979 | |
35 | MOG peptide 6 | 1776 | 1659 | |
0.974 | ||||
101 | MOG peptide 7 | 275 | 307 | |
101 | MOG peptide 8 | 247 | 215 | |
101 | MOG peptide 9 | 397 | 536 | |
101 | MOG peptide 10 | 1870 | 1335 | |
0.956 |
EYFP+ axons were counted in the right and left dorsal corticospinal tracts in L3 spinal cord cross-sections from normal, CFA control, and MOG peptide EAE EmxCre/RosaSTOP-EYFP mice. The regression coefficient r2 was close to 1 in each group, indicating little variance between the axon counts on the right and left side in either the control or MOG peptide EAE mice (Snedecor and Cochran, 1989).