Table 3.

Percentage volume change over 1 year in the AD group

Longitudinal change (%)p
Volumetric ROIs
    Accumbens−2.02<10−19
    Amygdala−3.79<10−19
    Brainstem−0.65<10−16
    Caudate−1.49<10−13
    Cerebellum GM−0.99<10−25
    Cerebellum WM−0.95<10−18
    Cerebral WM−1.42<10−30
    Hippocampus−3.75<10−35
    Pallidum−0.90<10−15
    Putamen−1.45<10−22
    Thalamus−1.51<10−28
Ventricular ROIs
    Lat vent10.35<10−28
    Inf lat vent16.26<10−33
    3rd ventricle6.82<10−21
    4th ventricle1.61<0.001
Surface ROIs
    Cingulate, caudal ant−1.14<10−17
    Cingulate, rostral ant−1.20<10−18
    Cingulate, posterior−1.57<10−21
    Cingulate, isthmus−1.54<10−23
    Frontal, superior−1.20<10−15
    Frontal, caudal middle−1.60<10−20
    Frontal, rostral middle−1.23<10−15
    Frontal, pars opercularis−1.31<10−18
    Frontal, pars triangularis−1.10<10−17
    Frontal, pars orbitalis−1.06<10−<10
    Frontal, lateral orbital−1.47<10−18
    Frontal, medial orbital−1.19<10−17
    Frontal, pole−1.38<10−10
    Parietal, precentral gyrus−0.69<10−10
    Parietal, postcentral gyrus−0.270.01
    Parietal, paracentral gyrus−0.76<10−11
    Parietal, superior−1.26<10−18
    Parietal, inferior−2.10<10−27
    Parietal, supramarginal−1.74<10−21
    Parietal, precuneus−1.61<10−24
    Temporal, parahippocampal−2.05<10−34
    Temporal, entorhinal−2.42<10−36
    Temporal, pole−2.54<10−26
    Temporal, superior−1.63<10−23
    Temporal, middle−2.87<10−31
    Temporal, inferior−2.97<10−32
    Temporal, transverse−0.59<10−6
    Temporal, banks sup temp sulc−2.53<10−28
    Temporal, fusiform−2.15<10−33
    Occipital, lateral−0.96<10−19
    Occipital, pericalcarine−0.16>0.01n.s.
    Occipital, lingual−0.67<10−15
    Occipital, cuneus−0.50<10−9

  • n.s., Not significant. Ant, Anterior; inf, inferior; lat, lateral; sulc, sulcus; sup, superior; temp, temporal; vent, ventricle.