Brain regions in which activity related to the age of the memory
| Brain region | Direction of effect | B.A. | Talairach coordinates | Vol. (mm3) | Effect size (η2) | ||
|---|---|---|---|---|---|---|---|
| LR | PA | IS | |||||
| Medial temporal lobe (p < 0.05 corrected, minimum cluster size = 375 mm3) | |||||||
| Right temporopolar Ctx./amygdala/insula/Inf. frontal G. | REC > REM | 30.4 | 8.4 | −9 | 8031 | 0.278 | |
| Left hippocampus/amygdala | REC > REM | −33.1 | 5.8 | −5.7 | 2375 | 0.267 | |
| Left hippocampus | REC > REM | −24.7 | −41.6 | 3.2 | 484 | 0.273 | |
| Whole brain (p < 0.05 corrected; minimum cluster size = 1766 mm3) | |||||||
| Left Inf. frontal G./temporopolar Ctx./insula/Sup. temporal G. | REC > REM | 47, 22 | −47.8 | 12.1 | −5.2 | 5156 | 0.284 |
| Bilateral rectal G./Inf. frontal G./subcallosal G. | REC > REM | 11 | 5.6 | 30.1 | −21.6 | 4359 | 0.284 |
| Left Inf. frontal G. | REC > REM | 45 | −56.4 | 12.7 | 21 | 3391 | 0.334 |
| Right Mid. frontal G. | REC > REM | 31.6 | 45.4 | 4.3 | 1875 | 0.297 | |
| Bilateral Med. frontal G./Sup. frontal G. | REC > REM | 9, 8 | −5.1 | 30.2 | 52.9 | 2188 | 0.261 |
| Right insula | REC > REM | 32.1 | 0.7 | 17.8 | 1812 | 0.290 | |
| Right insula/temporopolar Ctx./subcallosal G./amygdala/hippocampus | REC > REM | 30.1 | 7.1 | −10.8 | 5469 | 0.284 | |
| Right Inf. parietal lobule | REC > REM | 40 | 42.4 | −44.3 | 45.3 | 2328 | 0.292 |
| Bilateral brainstem/cerebellum | REC > REM | 3.6 | −42 | −25.8 | 11,297 | 0.297 | |
| Whole brain (p < 0.05 uncorrected; minimum cluster size = 313 mm3) | |||||||
| Right Sup. frontal G.* | REM > REC | 10 | 27.2 | 50.5 | 28.5 | 313 | 0.288 |
| Right Med. frontal G.* | REM > REC | 6 | 16.0 | 28.5 | 34.5 | 797 | 0.304 |
| Left Mid. frontal G. | REM > REC | 9 | −25.4 | 22.5 | 25.4 | 672 | 0.275 |
| Left Mid. frontal G. | REM > REC | 8 | −23.6 | 14.0 | 36.4 | 375 | 0.296 |
| Right Med. frontal G. | REM > REC | 6 | 13.7 | −6.4 | 56.0 | 407 | 0.284 |
| Right Sup. Temporal G. | REM > REC | 39 | 40.0 | −51.8 | 18.8 | 469 | 0.268 |
| Left Mid. Temporal G.* | REM > REC | −34.0 | −63.2 | 19.5 | 532 | 0.285 | |
| Right precuneus/cuneus* | REM > REC | 19 | 26.2 | −83.7 | 36.1 | 1016 | 0.265 |
Inf., Inferior; Mid., middle; Sup., superior; Med., medial; Ctx., cortex; G., gyrus; B.A., Brodmann area; Vol., volume; REC, recent memories; REM, remote memories; LR, left/right; PA, posterior/anterior; IS, inferior/superior. Talairach coordinates indicate the center of mass of each cluster. Asterisks, also illustrated in Figure 5.