Effect of K+ channel inhibitors on current density
| Drug | Target | Conc. (m) | Effect | Reference |
|---|---|---|---|---|
| Ba2+ | Kir and others | 10−3 | −12% | 1 |
| 4-Aminopyridine | Kv | 10−3 | −11% | 2 |
| XE991 | KCNQ | 10−4 | −19% | 3 |
| Glibenclamide | KATP channel | 10−5 | NC | 4 |
| Apamin | sK channels | 10−7 | NC | 5 |
| Clotrimazole | IKCa | 10−5 | NC | 6 |
| Iberiotoxin | KCa channels | 10−7 | NC | 7 |
| Extracellular low pH | Some K2P channels | 10−6 (pH 6) | NC | 8 |
| TEA | Many K+ channels | 3 × 10−3 | NC | 9 |
NC, No change; Conc., concentration.
1, Krapivinsky et al. (1998); 2, Wang et al. (2009); 3, Moser et al. (2008); 4, Quayle et al. (1997); 5, Stocker (2004); 6, Devor et al. (1997) and Dutta et al. (2009); 7, Tanaka et al. (2004); 8, Duprat et al. (1997, 2005), Rajan et al. (2000, 2005), and Morton et al. (2005); 9, Safronov et al. (1996), Cai et al. (1998), and Hadley et al. (2000).