Variable | HRa | 95% CI | p |
---|---|---|---|
TDP43(WT)-EGFP (n = 238) | |||
NCR | 0.982 | 0.969–0.996 | 0.0122 |
Cytoplasmic TDP43-EGFP (fluorescence intensity, a.u.) | 1.660 | 1.189–2.317 | 0.0029 |
Nuclear TDP43-EGFP (fluorescence intensity, a.u.) | 0.972 | 0.885–1.068 | NS |
TDP43(A315T)-EGFP (n = 272) | |||
NCR | 0.981 | 0.965–0.998 | 0.0278 |
Cytoplasmic TDP43-EGFP (fluorescence intensity, a.u.) | 1.346 | 1.080–1.678 | 0.0082 |
Nuclear TDP43-EGFP (fluorescence intensity, a.u.) | 0.972 | 0.872–1.084 | NS |
CI, Confidence interval; n, number of neurons; NS, not significant (p > 0.05); a.u., arbitrary unit.
↵aHR is reported in relation to SD of the NCR or TDP43-EGFP fluorescence intensity.