Table 1.

Pearson's correlation coefficient values (R) obtained from the linear regression analyses correlating spinal cord mRNA expression levels of TGF-β1, BMP-2, BMP-7, activin, SMAD4, TAK1, and BAMBI with the expression of genes encoding POMC, PENK, and PDYN

TGF-β1BMP-2BMP-7ActivinSMAD-4TAK-1BAMBI WT
WTKOWTKOWTKOWTKOWTKOWTKO
POMC0.65**0.54*0.47*0.48*0.57*0.75***0.54*0.72***0.300.67**0.410.72***−0.62*
PENK0.76***0.65**0.69**0.65**0.80***0.71***0.58*0.63**0.64**0.80***0.73***0.70***−0.51*
PDYN0.71***0.72***0.75***0.80***0.68***0.83***0.61**0.68**0.390.68***0.45*0.77***−0.54*
  • WT, Wild type; KO, knock-out.

  • *p < 0.05,

  • **p < 0.01, and

  • ***p < 0.001.