Table 1.

Novel versus practiced encoding activity voxel clusters

Cluster labels	Direction of signal	Hemisphere	Voxels (3.2 mm³)	Talairach coordinate x	Talairach coordinate y	Talairach coordinate z	Areas
aPFC	P > N	Left	31	−22.3	48.1	18.5	10
DLPFC	N > P	Right	29	29.6	26.5	35.3	9
IPL	N > P	Left	51	−52	−27.2	25.7	40
PCC	P > N	Both	40	−2	−46.8	29.7	31
M1/S1/S2	N > P	Left	39	−18.3	−29.3	66.7	4, 3, 5
Fusiform/cerebellum	N > P	Right	24	25.7	−37.8	−19.7	20, 36
ACC	N > P	Left	24	−11.5	1.4	28.7	24
M1/S1	N > P	Right	24	41.7	−25.4	58	3, 4
VLPFC	N > P	Left	23	−46.8	29.3	−4.2	47, 45
BG (Medial globus pallidus and putamen)	N > P	Left	16	−17	−2.8
aTL	P > N	Right	15	51.1	−2.5	−24.8	20, 21
IFJ	N > P	Right	15	27.8	0.5	32	9, 6
PMC	N > P	Right	15	22.9	−13.4	47.5	6
VLPFC	N > P	Right	14	48.9	25.5	−0.7	47, 45
PMC	N > P	Left	14	−32	−15.5	60.5	6
Cuneus	N > P	Left	13	−10.2	−62.6	5.6	18, 19

The contrast was defined by a condition × time (novel vs practiced × 11 time points) interaction (p < 0.05, FWE corrected for lateral PFC, FDR corrected for all other voxels). P > N, Practiced significantly greater than novel; N > P, novel significantly greater than practiced; ACC, anterior cingulate cortex; BG, basal ganglia.