Quantification of electrophysiological properties of 5-HT3AR-expressing neurons in layer 2/3 (n = 80)
| LS1 | LS2 | bNA1 | bNA2 | IS | dNFS3 | fAD | |
|---|---|---|---|---|---|---|---|
| RMP (mV) | −61.2 ± 5.8 | −60.5 ± 7.0 | −63 ± 4.3 | −60.2 ± 5.7 | −58.4 ± 5.9 | −65 ± 6.3 | −56.9 ± 7.0 |
| R m (MΩ) | 329 ± 89 | 285 ± 101 | 332 ± 124 | 369 ± 143 | 406 ± 132 | 631 ± 310 | 459 ± 179 |
| τm (ms) | 17.3 ± 6.5 | 19.3 ± 5.8 | 17.5 ± 8.5 | 19.4 ± 8.3 | 20.1 ± 7.1 | 27.7 ± 12.3 | 26.4 ± 9.7 |
| Spike threshold (mV) | −38.2 ± 5.4 | −36.9 ± 5.1 | −35.5 ± 4.5 | −36.1 ± 3.8 | −39.8 ± 6.3 | −42.2 ± 6.1 | −38.3 ± 4.9 |
| Spike width (ms) | 1.4 ± 0.5 | 1.4 ± 0.4 | 1.4 ± 0.6 | 1.4 ± 0.4 | 1.2 ± 0.4 | 1.3 ± 0.3 | 1.1 ± 0.3 |
| AHP amplitude (mV) | −19.3 ± 5.2 | −18.2 ± 3.9 | −16.1 ± 5.1 | −14.4 ± 4.6 | −13.0 ± 0.4 | −15.3 ± 3.3 | −12.2 ± 3.4 |
| tAHP (ms) | 23.1 ± 4.8 | 24.8 ± 7.9 | 50.3 ± 11.9 | 24.9 ± 8.5 | 14.2 ± 5.2 | 14.1 ± 9.8 | 18.1 ± 9.9 |
| Delay to spike (ms) | 376.3 ± 79.8 | 224.8 ± 130.1 | 70.3 ± 21.4 | 75.4 ± 41.4 | 259.5 ± 120.5 | 14.1 ± 9.8 | 18.1 ± 9.9 |
| Max frequency (Hz) | 79.3 ± 30.1 | 59.2 ± 18.4 | 52.6 ± 14.9 | 61.5 ± 28.4 | 84.9 ± 16.5 | 81.3 ± 21.4 | 85.7 ± 21.5 |
| Adaptation (%) | 51.3 ± 14.5 | 53.9 ± 16.3 | 63.7 ± 18.2 | 59.4 ± 21.4 | 41.5 ± 11.6 | 36.3 ± 9.8 | N/A |
For an explanation of the parameters, see Materials and Methods.