Distribution of leptin-activated and insulin-inhibited POMC neurons in the retrochiasmatic area and the arcuate nucleus
| Region | Recorded cells | Leptin-activated cells | Percentage of leptin-activated cells | Recorded cells | Insulin-inhibited cells | Percentage of insulin-inhibited cells |
|---|---|---|---|---|---|---|
| RCA | 17 | 4 | 23.5 | 19 | 7 | 36.8 |
| Arc1 | 10 | 2 | 20.0 | 7 | 2 | 25.0 |
| Arc2 | 12 | 8 | 66.7 | 9 | 1 | 11.1 |
| Arc3 | 7 | 2 | 28.6 | 5 | 0 | 0.0 |
Values represent the number and percentage of POMC neurons (RCA and Arc) that were targeted and either depolarized or hyperpolarized in the presence of leptin and insulin, or remained unchanged. Arc1, Arcuate nucleus of the hypothalamus, rostral level; Arc2, arcuate nucleus of the hypothalamus, intermediate level; Arc3, arcuate nucleus of the hypothalamus, caudal level; RCA, retrochiasmatic area.