Table 1.
Open and burst durations for receptors with different numbers of active coupling regions
| No. of active regions | Subunit (number in the arrangement) | Receptor | pA | τO (ms) | τB (ms) | n | |
|---|---|---|---|---|---|---|---|
| 5 | A-HC (5) | I-LC (0) |  | 9.9 ± 0.6 | 8.8 ± 2.3 | 17.8 ± 5.0 | 15 |
| 4 | A-HC (4) | I-LC (1) |  | 7.9 ± 0.3 | 7.0 ± 1.2 | 14.0 ± 3.3 | 14 |
| 3 | A-HC (3) | I-LC (2) |  | 5.8 ± 0.3 | 5.5 ± 2.8 | 10.7 ± 5.2 | 13 |
| 2 | A-LC (2) | I-HC (3) |  | 6.1 ± 0.3 | 4.9 ± 1.1 | 7.6 ± 1.5 | 10 |
| 1 | A-LC (1) | I-HC (4) |  | 8.1 ± 0.1 | 3.0 ± 0.8 | 7.4 ± 3.0 | 6 |
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Single-channel currents were recorded from cells transfected either with A-HC plus I-LC or with A-LC plus I-HC subunit cDNAs. Possible subunit arrangements for each channel amplitude class are shown. In the schemes, the black cross indicates inactive coupling region, and high- and low-conductance forms are shown as black and gray circles, respectively. τO and τB correspond to the longest duration component of the open and burst duration histograms, respectively. Results are shown as mean ± SD for each amplitude class for the indicated number of patches, n.