Effects of 0.5 mg/kg amphetamine, intracranial CTAP into the NAc shell subregion and their combination, or intracranial DAMGO into the NAc shell subregion on measures of attentional function, compulsivity, and motivation in the 5-CSRTT
| Treatment (systemic–local) | Accuracy (%) | Perseverative responses | Response latency (ms) | Omissions | Feeder latency (ms) |
|---|---|---|---|---|---|
| Vehicle–vehicle | 86.7 ± 2.9 | 12.4 ± 2.0 | 334 ± 11 | 15.3 ± 2.1 | 2016 ± 351 |
| Vehicle–CTAP (3 μg) | 84.1 ± 2.5 | 13.5 ± 3.7 | 330 ± 8 | 19.0 ± 3.4 | 2235 ± 367 |
| AMPH–vehicle | 73.7 ± 3.6** | 11.7 ± 4.0 | 321 ± 14 | 16.5 ± 1.6 | 2274 ± 483 |
| AMPH–CTAP (1 μg) | 80.2 ± 3.1# | 8.3 ± 2.3 | 317 ± 10 | 19.2 ± 2.5 | 2227 ± 499 |
| AMPH–CTAP (3 μg) | 80.9 ± 2.7# | 7.9 ± 2.9 | 351 ± 13 | 25.1 ± 4.2 | 2037 ± 525 |
| Vehicle | 86.7 ± 2.0 | 10.2 ± 3.4 | 342 ± 15 | 14.9 ± 1.2 | 2147 ± 477 |
| DAMGO (0.125 μg) | 84.1 ± 0.9 | 10.6 ± 3.8 | 339 ± 19 | 17.2 ± 3.4 | 1759 ± 461 |