Behavioral data
| Crl:Wi | B&K:Wi | Statistical analysis | |
|---|---|---|---|
| Open field | n = 13 | n = 13 | |
| Number of line crossings in 20 min | 260.3 ± 22.1 | 204.4 ± 18.5 | t(24) = 1.94, p > 0.05 |
| % outside/total line crossings | 85.8 ± 1.0 | 92.5 ± 1.4 | t(24) = 3.92, p < 0.005 |
| % inside/total line crossings | 14.2 ± 1.0 | 7.5 ± 1.4 | t(24) = 3.92, p < 0.005 |
| Total number of rears | 95.5 ± 6.3 | 68.8 ± 5.5 | t(24) = 3.27, p < 0.01 |
| % outside/total of rears | 92.8 ± 1.1 | 97.3 ± 0.6 | t(24) = 3.58, p < 0.01 |
| % inside/total of rears | 7.2 ± 1.1 | 2.7 ± 0.7 | t(24) = 3.58, p < 0.01 |
| Elevated plus maze | n = 13 | n = 14 | |
| % time spent in closed arms | 45.9 ± 2.7 | 48.3 ± 2.7 | t(25) = 0.61, p > 0.1 |
| % time spent in centre | 36.4 ± 2.8 | 46.5 ± 2.3 | t(25) = 2.83, p < 0.01 |
| % time spent in open arms | 17.7 ± 2.6 | 5.2 ± 1.8 | t(25) = 4.00, p < 0.001 |
| Total number of entries | 9.7 ± 0.5 | 8.3 ± 0.3 | t(25) = 2.24, p < 0.05 |
| Number of closed arm entries | 6.1 ± 0.3 | 7.3 ± 0.3 | t(25) = 2.62, p < 0.05 |
| Number of open arm entries | 3.6 ± 0.3 | 1.0 ± 0.3 | t(25) = 5.58, p < 0.001 |
| Latency to first closed arm entry (s) | 24.5 ± 5.3 | 21.7 ± 6.4 | t(25) = 0.33, p > 0.1 |
| Latency to first open arm entry (s) | 38.1 ± 17.3 | 182.5 ± 33.0 | t(25) = 3.79, p < 0.005 |
Data from open field (top) and elevated plus maze (bottom) behavioral assays on matched 9- to 11-week-old rats from sensitive (Crl:Wi) and insensitive (B&K:Wi) strains. Values are given as the mean ± SEM and t (degrees of freedom) and p values from Student's t test.