Basic electrode and membrane properties from whole-cell recordings
| Treatment group | Electrode (MΩ) | Access resistance (MΩ) | Capacitance (pF) | Holding current (pA) | n |
|---|---|---|---|---|---|
| Control | 2.42 ± 0.06 | 10.01 ± 0.54 | 60.84 ± 4.79 | 147.91 ± 11.92 | 18 |
| Rapamycin, 1 h | 2.45 ± 0.10 | 9.73 ± 0.57 | 51.37 ± 3.62 | 113.80 ± 12.18 | 4 |
| Rapamycin, 24 h | 2.45 ± 0.08 | 10.44 ± 0.66 | 60.15 ± 3.69 | 133.26 ± 7.50 | 20 |
| Rapamycin, 4 d | 2.61 ± 0.07 | 10.04 ± 0.77 | 54.47 ± 2.86 | 113.74 ± 11.09 | 20 |
| Nimodipine | 2.55 ± 0.08 | 9.13 ± 0.33 | 53.07 ± 1.02 | 103.93 ± 17.42 | 12 |
| Rapamycin (4 d) + Nimodipine | 2.47 ± 0.08 | 8.97 ± 0.44 | 53.69 ± 1.75 | 107.77 ± 19.18 | 10 |
| siRNA FKBP | 2.62 ± 0.06 | 9.03 ± 0.45 | 57.47 ± 2.63 | 131.63 ± 12.02 | 23 |
| siRNA nontargeted | 2.52 ± 0.04 | 9.25 ± 0.060 | 57.86 ± 3.16 | 134.66 ± 16.58 | 19 |
| siRNA vehicle | 2.43 ± 0.05 | 9.05 ± 0.053 | 57.88 ± 2.90 | 128.20 ± 21.63 | 23 |
No differences in basic properties were observed across conditions; means ± SEM.