Fractional anisotropy | Mean diffusivity (mm2/s) | |||||||
---|---|---|---|---|---|---|---|---|
Intercept | Age (×10−2) | Age2 (×10−3) | Sexa | Intercept (×10−3) | Age (×10−5) | Age2 (×10−6) | Sex (×10−5)a | |
Commissural tracts | ||||||||
Genu of corpus callosum | 0.52 <0.001 | 0.51 <0.001 | −0.13 <0.001 | n.s. | 0.88 <0.001 | −0.87 <0.001 | 0.18 <0.001 0.16 0.004 | n.s. |
Body of corpus callosum | 0.48 <0.001 | 0.60 <0.001 | −0.14 <0.001 | n.s. | 0.97 <0.001 | −0.97 <0.001 | n.s. | |
Splenium of corpus callosum | 0.53 <0.001 | 0.52 0.001 | −0.11 0.013 | 0.013 0.001 | 0.93 <0.001 | −1.36 <0.001 | 0.31 <0.001 | n.s. |
Projection tracts | ||||||||
Corticospinal tractsb | 0.86 <0.001 | −0.20 <0.001 | n.s. | 1.2 0.007 | ||||
Left CSTb | 0.43 <0.001 | 1.03 <0.001 | −0.24 <0.001 | −0.009 0.004 | ||||
Right CSTb | 0.46 <0.001 | 0.60 <0.001 | −0.13 <0.001 | −0.011 0.001 | ||||
Association tracts | ||||||||
Cingulum | 0.43 <0.001 | 0.54 <0.001 | −0.07 0.038 | −0.014 <0.001 | 0.88 <0.001 | −0.94 <0.001 | 0.17 <0.001 | 0.89 0.021 |
Inferior longitudinal fasciculus | 0.41 <0.001 | 0.47 <0.001 | −0.01 0.001 | n.s. | 0.93 <0.001 | −0.79 <0.001 | 0.16 <0.001 | n.s. |
Inferior fronto-occipital fasciculus | 0.45 <0.001 | 0.68 <0.001 | −0.13 <0.001 | n.s. | 0.88 <0.001 | −0.68 <0.001 | 0.15 <0.001 | n.s. |
Superior longitudinal fasciculus | 0.42 <0.001 | 0.67 <0.001 | −0.14 <0.001 | −0.005 0.027 | 0.85 <0.001 | −0.89 <0.001 | 0.17 <0.001 | n.s. |
Superior fronto-occipital fasciculus | 0.41 <0.001 | 0.53 <0.001 | −0.13 <0.001 | n.s. | 0.82 <0.001 | −0.62 <0.001 | 0.11 0.002 | 0.81 0.017 |
Uncinate fasciculus | 0.37 <0.001 | 0.44 <0.001 | −0.08 0.011 | −0.009 0.002 | 0.90 <0.001 | −0.58 <0.001 | 0.10 <0.001 | n.s. |
CST, Corticospinal tract; n.s., not significant.
↵aPositive values for sex term indicate higher FA or MD values in females.
↵bThe CST was assessed separately for each hemisphere for FA measures, where there were significant differences in the age and age2 parameters; for MD, there were no significant differences, so hemispheres were combined.