Comparison of flatworm and vertebrate Cavα identity
| Dj | Sm | Hs | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cav1A | Cav1B | Cav1A | Cav1B | Cav2A | Cav1.1 | Cav1.2 | Cav1.3 | Cav1.4 | Cav2.3 | Cav3.1 | |
| Cav1 Dj | |||||||||||
| Cav1A | 52% | 57% | 54% | 39% | 49% | 48% | 49% | 48% | 38% | 23% | |
| Cav1B | 50% | 61% | 34% | 49% | 46% | 47% | 48% | 37% | 22% | ||
Sequences were aligned using the BLOSUM62 scoring matrix (ClustalW MSA), and amino acid identities were computed. Sm.Cav1 was renamed Sm.Cav1A, owing to the in silico predication of a second Cav1 subunit in Schistosoma mansoni (named Sm.Cav1B, GenBank #CAZ34413.1). Subunits for which complete coding sequences have been biologically verified are shown in bold. Groupings with the highest identity are underlined. The following accession numbers were used: Schistosoma mansoni (Sm): Sm.Cav1A (AF361884), Sm.Cav1B (CAZ34413.1), Sm.Cav2A (AF361883); Homo sapiens (Hs): Hs.Cav1.1 (Q13698), Hs.Cav1.2 (Q13936), Hs.Cav1.3 (Q1668), Hs.Cav1.4 (O60840), Hs.Cav2.3 (Q15878), Hs.Cav3.1 (O43497).