Monoamines and their metabolite contents in hippocampus
| WT (n = 16) | STX1A−/− (n = 6) | |
|---|---|---|
| NA (ng/mg protein) | 4.56 ± 0.64 | 3.52 ± 1.07 |
| MHPG (ng/mg protein) | 0.44 ± 0.04 | 0.37 ± 0.12 |
| MHPG/NA | 0.09 ± 0.01 | 0.13 ± 0.03 |
| DA (ng/mg protein) | 2.47 ± 0.33 | 3.57 ± 0.72 |
| DOPAC (ng/mg protein) | 1.17 ± 0.12 | 0.86 ± 0.16 |
| DOPAC/DA | 0.37 ± 0.03 | 0.19 ± 0.03** |
| 5-HT (ng/mg protein) | 5.74 ± 0.36 | 8.23 ± 0.40** |
| 5-HIAA (ng/mg protein) | 1.42 ± 0.30 | 1.21 ± 0.10 |
| 5-HIAA/5-HT | 0.25 ± 0.05 | 0.15 ± 0.01 |
Data shown are mean ± SE.
↵**p < 0.01.