R6/2 mice have increased susceptibility to audiogenic seizures
| Group | Clinical seizures | ||
|---|---|---|---|
| Number of mice with seizures | Racine scale | Deaths | |
| WT | 1 | 1 | 0 |
| 1 | 2 | ||
| R6/2 | 2 | 3 | 2 |
| 4 | 4 | ||
| 2 | 5 | ||
Shown are each mouse that developed seizures of eight mice per group (WT and R6/2, n = 16). Note that all R6/2 mice had seizures with varying intensities; only two WT mice had abnormal behavior induced by the siren that met the criteria for ictal events.