Table 3.

Brain clusters showing interaction between APOE genotype and gender and clusters showing differences in subsequent post hoc comparisons

Brain networkContrastBrain regionCluster size (voxels)Peak MNI coordinates (mm)
xyz
Posterior DMNAPOE × gender interactionRH cuneal cortex/precuneus7312−7232
LH precuneus490−7038
Posterior DMNFemale ϵ3 homozygotes > female ϵ4 carriersRH cuneal cortex/precuneus/posterior cingulate cortex219318−7432
LH lateral occipital cortex52−44−6416
LH supramarginal gyrus36−50−4642
LH middle frontal gyrus13−381250
Posterior DMNMale ϵ3 homozygotes > male ϵ4 carriersLH superior parietal lobule16−28−4860
Posterior DMNMale ϵ4 carriers > female ϵ4 carriersRH angular gyrus8562−5040
LH lateral occipital cortex30−52−7440
RH cuneal cortex/precuneus2112−7432
  • LH, Left hemisphere; RH, right hemisphere.