Common functional categories enriched with rearing condition differentially methylated genes in both PFC and T cells
| Pathways and categories | Fold enrichment | p value | Genes name more or less methylated in SPR |
|---|---|---|---|
| PFC | |||
| Immune response | 1.62 | 2.0E−03 | C8A, CCR9, CD8A, CIITA, CSF3, DMBT1, FCGR3A, ICOS, IFI35, IFNB1, IL15, IL1A, IL20, IL23R, IL31RA, IL7, IRF7, LTB, SEMA4D, SH2D1A, ZAP70, CCL11, CD55, CXCL3, DEFB127, HLA-DOB, HLA-DQB1, IFIT1, IL2, IL8, MASP1, MNDA, PGLYRP3, RBM4, SPN, TBK1, TCF7, TNFSF12 |
| Transcription from RNA polymerase II promoter | 1.82 | 1.0E−04 | FOXO4, GLI2, IRF7, MNAT1, MTA2, MYEF2, MYF5, POLR2A, RUNX1, TAF7, ASCL1, BLZF1, BRD8, CCNT1, ETV3, GTF2E1, GTF2F2, GTF2I, HOXC6, JAZF1, MAML2, MITF, MLL, MSC, MTF1, NFYC, PPARGC1A, SMAD1, SUFU, TAF5L, TARBP1, TCF7, TFAP2A, TRAK1, ZBTB32, ZNF238 |
| Response to stimulus | 1.66 | 1.0E−04 | ANXA5, AOC3, C8A, CYBB, DUSP10, ERCC1, FABP4, FBLN5, FGB, FGF7, FOXN3, FOXO4, GP5, IL1A, IL20, IL23R, IL25, IRF7, NINJ2, RUNX1, ADRB1, AHSA2, CCL11, CD55, CMA1, CXCL3, EDN1, EIF2AK3, EIF2S1, HSP90AA1, HSPB7, HSPBAP1, IL8 KPTN, MAPKAPK5, MASP1, MTF1, PDIA5, PPARGC1A, RBM4, SERP1, SMAD1, SPN, TAOK2, TP53I11, TXNDC4, VPS45, WDR33 |
| T cells | |||
| Transcription | 2.30 | 1.0E−03 | POLR2B, EDA2R, NFKB2, HOXC10, TBL1XR1, CD3EAP, SSRP1, CHD7, ZNF724P, TAF4B, ZNF236, TAF6L, ZNF569, APBB1, ABCA13, ZBTB39, A2D681 |
| Immune response | 3.16 | 1.0E−02 | CXCL9, CD3EAP, IL16, PRG2, IGLL1, PDCD1LG2 |
| Response to stimulus | 1.83 | 2.0E−02 | IFNGR2, CXCL9, CD3EAP, IL16, SSRP1, PRG2, SLC24A5, IGLL1, CNGA2, PDCD1LG2, OR1B1, A2D681, DEFB129, SERPINB13 |