Patient | Age | Sex | Disease duration (year) | STN-DBS duration (month) | UPDRS III Off-DBS | UPDRS III On-DBS | UPDRS improvement (%) | levodopa eq. dosage (mg/d) | Stimulation parameters |
---|---|---|---|---|---|---|---|---|---|
1 | 57 | F | 13 | 14 | 28 | 8 | 71 | 300 | L1: 2.9 V, 60 μs,130 Hz |
R6: 3.5 V, 60 μs,130 Hz | |||||||||
2 | 60 | M | 14 | 17 | 23 | 5 | 78 | 400 | L2: 2.5 V, 60 μs,130 Hz |
R6: 3.2 V, 90 μs,130 Hz | |||||||||
3 | 61 | M | 9 | 25 | 39 | 8 | 79 | 300 | L3: 3.5 V, 60 μs,130 Hz |
R6: 3.2 V, 90 μs,130 Hz | |||||||||
4 | 52 | M | 15 | 39 | 28 | 10 | 64 | 300 | L2: 3.0 V, 60 μs,130 Hz |
R6: 3.1 V, 60 μs,130 Hz | |||||||||
5 | 59 | M | 8 | 3 | 27 | 13 | 52 | 700 | L2: 3.5 V, 60 μs,70 Hz |
R5: 3.7 V, 60 μs,70 Hz | |||||||||
6 | 48 | F | 17 | 60 | 49 | 22 | 55 | 150 | L3: 2.6 V, 90 μs,160 Hz |
R6: 3.1 V, 60 μs,160 Hz | |||||||||
7 | 61 | M | 18 | 6 | 31 | 11 | 65 | 550 | L2: 2.6 V, 60 μs,130 Hz |
R6: 3.0 V, 6.0 μs,130 Hz | |||||||||
8 | 61 | M | 14 | 48 | 31 | 15 | 52 | 175 | L3: 2.5 V, 60 μs,130 Hz |
R7: 3.0 V, 60 μs,130 Hz | |||||||||
9 | 65 | M | 13 | 36 | 25 | 6 | 76 | 500 | L1: 2.9 V, 90 μs,160 Hz |
R5: 2.7 V, 90 μs,160 Hz | |||||||||
10 | 58 | F | 14 | 38 | 17 | 8 | 53 | 900 | L2: 5.0 V, 60 μs,70Hz |
R5: 5.0 V, 60 μs,70 Hz | |||||||||
11 | 51 | M | 10 | 3 | 29 | 8 | 72 | 350 | L2: 2.3 V, 60 μs,130 Hz |
R6: 2,7 V, 60 μs,130 Hz | |||||||||
12 | 69 | F | 13 | 6 | 22 | 12 | 45 | 400 | L2: 3.2 V, 60 μs,130 Hz |
R6: 3.1 V, 60 μs,130 Hz | |||||||||
13 | 68 | M | 28 | 35 | 13 | 3 | 77 | 0 | L2: 3.0 V, 60 μs,130 Hz |
R6: 2.8 V, 60 μs,130 Hz | |||||||||
14 | 66 | M | 17 | 41 | 30 | 17 | 43 | 300 | L2: 3.0 V, 60 μs,130 Hz |
R6: 3.5 V, 90 μs,130 Hz | |||||||||
μ ± σ | 59.7 ± 6.3 | 14.5 ± 4.9 | 26.5 ± 18.5 | 28 ± 8.8 | 10.4 ± 5.1 | 63 ± 12 | 380 ± 230 |
STN stimulation parameters: pulse height, width, and frequency. Contact points of the stimulation tetrodes are numbered from L0 to L3 (left side, L) and R4 to R7 (right side, R) from ventralmost to dorsalmost. These contacts are spaced by 2 mm. Average and SD of the numerical data across the group are provided at the bottom of each column, when relevant. Levodopa equivalent calculation: 100 mg levodopa = 10 mg bromocriptine = 6 mg ropinirole = 1 mg pergolide = 60 mg piribedil = 0.7 mg pramipexole (Thobois, 2006).