Table 1.

RM ANOVA results for Crtl1 ko mice vs Crtl1-Tg and wt mice

Main effect or interactionFpSimple main effects
Discrimination ratio with delays of 1 min, 3 h, 24 h, 48 h
    GenotypeF(2,25) = 32.7<0.001Crtl1 ko vs wt: F(1,21) = 21.34, p <0.001
Crtl1 ko vs Crtl1-Tg: F1,16 = 18.2, p <0.001
Crtl1-Tg vs wt: F > 1, p = 0.842
    DelayF(3,75) = 31.1<0.001
    Genotype × delayF(6,75) = 9.2= 0.003Crtl1 ko vs wtCrtl1-Tg vs wt
1 min: F <1, p = 0.1211 min: F <1, p = 0.778
3 h: F(1,21) = 4.1, p = 0.0143 h: F <1, p = 0.971
24 h: F(1,21) = 4.5, p = 0.03024 h: F <1, p = 0.882
48 h: F(1,21) = 10.2, p <0.00148 h: F <1, p = 0.612
Discrimination ratio with delays of 24 h and 48 h before and after chABC treatment
    GenotypeF(1,9) = 9.1= 0.015Crtl1 ko vs wt
Before chABC: F(1,9) = 18.9, p = 0.009;
After chABC: F <1, p = 0.751
    DelayF <1= 0.410
    chABCF(1,9) = 2.1= 0.179Before vs after treatment
wt: F(1,9) = 5.7, p = 0.041;
Crtl1 ko: F <1, p = 0.664
    chABC × genotypeF(1,9) = 4.3= 0.043
    chABC × genotype × delayF <1= 0.757