Dominant frequencies (mean ± SEM) of auditory-evoked powers in hippocampal areas CA1 and CA3 and the LA before, during, and after chronic stress
| Dominant frequency (Hz) | Stress-induced change in power compared with before stress (Hz) at p = 0.05 | |||||
|---|---|---|---|---|---|---|
| CA1 | CA3 | LA | CA1 | CA3 | LA | |
| Before stress | 27.7 ± 1.3 | 23.4 ± 1.8 | 19.8 ± 1.5 | |||
| 1 h + (1 d & 2 d stress) | 24.5 ± 3.2 | 19.6 ± 2.0 | 25.4 ± 1.0* | 14–34 ↑ | 14–24 ↑ | 20–40 ↑ |
| 24 h + (1 d & 2 d stress) | 27.3 ± 1.4 | 24.1 ± 2.9 | 26.6 ± 2.2** | ns | ns | 21–32 ↑ |
| 24 h + (9 d & 10 d stress) | 23.0 ± 1.5 | 21.5 ± 2.0 | 33.5 ± 1.8*** | ns | ns | 30–34 ↑ |
| Stress-free recovery | 25.7 ± 3.6 | 27.2 ± 1.9 | 34.7 ± 1.3*** | 23–37 ↓ | 14–39 ↓ | ns |
↵*p < 0.05,
↵**p < 0.01,
↵***p < 0.001 compared with the values before stress. There was a significant main effects of stress (stress-induced change in power) in all three areas on recording time points (CA1, F(4,24) = 9.45, p < 0.001; CA3, F(4,24) = 10.19, p < 0.001; LA, F(4,24) = 7.37, p < 0.001) and frequency (CA1, F(300,1800) = 15.07, p < 0.001; CA3, F(300,1800) = 11.75, p < 0.001; LA, F(300,1800) = 3.325, p < 0.001) (see Materials and Methods). Arrows indicate directions of change; ns, not significant.