ERG intensity–response parameters
| Scotopic a-wave | Scotopic b-wave | |||||
|---|---|---|---|---|---|---|
| I1/2 (cd · s m−2) | Rmax (μV) | n (I1/2) | I1/2 (cd · s m−2) | Rmax (μV) | n (I1/2) | |
| PhLP1+/+Cre+ (n = 7) | 0.60 ± 0.11 | 337 ± 26 | 0.87 ± 0.10 | 0.14 ± 0.04 | 806 ± 48 | 0.48 ± 0.03 |
| PhLP1F/FCre+ (n = 12) | 10.7 ± 3.1** | 178 ± 23*** | 0.59 ± 0.05* | 0.86 ± 0.19** | 494 ± 41*** | 0.90 ± 0.10** |
Half-saturating light intensity (I1/2), maximal response amplitudes (Rmax), and Hill coefficients (n) from fits of the data in Figure 6, F and G, are given for the scotopic a-wave and b-wave for PhLP1+/+Cre+ and PhLP1F/FCre+ mice. Values are means ± SEM.
↵*p < 0.05;
↵**p < 0.01;
↵***p < 0.001 all compared to wild type values.