Table 2.

Cocaine > pleasant responsiveness as a function of DAT1 and cocaine urine status

Variable	Diagnosis main effect	DAT1 main effect	Interaction	Follow-up comparisons
Cocaine > pleasant LPPs	F_(2,105) = 1.61	F_(1,105) = 0.03	F_(2,105) = 4.27^*	9R-allele: CUD⁺ > CUD⁻: t₍₂₁₎ = 2.49^*
Cocaine > pleasant LPPs	F_(2,105) = 1.61	F_(1,105) = 0.03	F_(2,105) = 4.27^*	10R/10R: CUD⁺ > CUD⁻: t₍₄₀₎ = −1.42
Cocaine > pleasant picture valence	F_(2,106) = 13.71^***	F_(1,106) = 0.58	F_(2,106) = 1.58	9R-allele: CUD⁺ > CUD⁻: t₍₂₃₎ = 3.20^**
Cocaine > pleasant picture valence	CUD⁺ > CUD⁻ > control	F_(1,106) = 0.58	F_(2,106) = 1.58	10R/10R: CUD⁺ > CUD⁻: t_(43.0) = 0.89
Cocaine > pleasant picture arousal	F_(2,106) = 6.31^**	F_(1,106) = 0.04	F_(2,106) = 0.09	9R-allele: CUD⁺ > CUD⁻: t₍₂₃₎ = 0.35
Cocaine > pleasant picture arousal	Both CUD > control	F_(1,106) = 0.04	F_(2,106) = 0.09	10R/10R: CUD⁺ > CUD⁻: t₍₄₃₎ = 0.14
Cocaine > pleasant probabilistic choice	F_(2,99) = 13.07^***	F_(1,99) = 0.93	F_(2,99) = 1.76	9R-allele: CUD⁺ > CUD⁻: t₍₂₁₎ = 2.19^*
Cocaine > pleasant probabilistic choice	Both CUD > control	F_(1,99) = 0.93	F_(2,99) = 1.76	10R/10R: CUD⁺ > CUD⁻: t_(35.8) = −0.62
Cocaine > pleasant explicit choice	F_(2,92) = 2.40	F_(1,92) = 0.83	F_(2,92) = 2.45	9R-allele: CUD⁺ > CUD⁻: t₍₂₀₎ = 1.18
Cocaine > pleasant explicit choice	F_(2,92) = 2.40	F_(1,92) = 0.83	F_(2,92) = 2.45	10R/10R: CUD⁺ > CUD⁻: t₍₃₆₎ = −1.53
Cocaine > fixation fMRI lateral OFC	F_(2,90) = 5.59^**	F_(1,90) = 3.62	F_(2,90) = 4.74^*	9R-allele: CUD⁺ > CUD⁻: t₍₂₀₎ = 2.34^*
Cocaine > fixation fMRI lateral OFC	CUD⁺ and control > CUD⁻	F_(1,90) = 3.62	F_(2,90) = 4.74^*	10R/10R: CUD⁺ > CUD⁻: t₍₃₂₎ = −0.23
Cocaine > fixation fMRI medial OFC	F_(2,90) = 0.96	F_(1,90) = 2.59	F_(2,90) = 0.82	9R-allele: CUD⁺ > CUD⁻: t₍₂₀₎ = −0.19
Cocaine > fixation fMRI medial OFC	F_(2,90) = 0.96	F_(1,90) = 2.59	F_(2,90) = 0.82	10R/10R: CUD⁺ > CUD⁻: t₍₃₂₎ = 1.32
Cocaine > fixation fMRI ventral striatum	F_(2,90) = 0.98	F_(1,90) = 0.70	F_(2,90) = 0.04	9R-allele: CUD⁺ > CUD⁻: t₍₂₀₎ = −0.47
Cocaine > fixation fMRI ventral striatum	F_(2,90) = 0.98	F_(1,90) = 0.70	F_(2,90) = 0.04	10R/10R: CUD⁺ > CUD⁻: t₍₃₂₎ = −1.37
Cocaine responsiveness across modalities	F_(2,114) = 16.64^***	F_(1,114) = 0.85	F_(2,114) = 4.23^*	9R-allele: CUD⁺ > CUD⁻: t₍₂₅₎ = 2.95^**
Cocaine responsiveness across modalities	Both CUD > control	F_(1,114) = 0.85	F_(2,114) = 4.23^*	10R/10R: CUD⁺ > CUD⁻: t₍₄₄₎ = −0.68

↵*p < 0.05,
↵**p < 0.01,
↵***p < 0.001.