Neuronal number in medial entorhinal cortex: stereologya
| Age | Layer | WT | APP | APP-BDNF |
|---|---|---|---|---|
| 2–3 mo | Total (layer II-VI) | 139,100 ± 3310 | 128,455 ± 5560 (−7.6%)* | — |
| 7.5 mo | Total (layer II-VI) | 130,365 ± 10,814 | 109,092 ± 6529 (−16.3%)*,** | 123,187 ± 9814 (−5.5%) |
| 7.5 mo | Layer II | 32,057 ± 3462 | 25,109 ± 3523 (−21.9%)*,** | 28,543 ± 2846 (−11.1%) |
| 7.5 mo | Layer III | 46,096 ± 4654 | 38,469 ± 4833 (−16.5%)*,** | 44,524 ± 5289 (−3.4%) |
| 7.5 mo | Layer V-VI | 52,211 ± 5599 | 45,604 ± 3856 (−12.7%)*,** | 50,119 ± 4999 (−4.0%) |