Table 2.

[Ca2+]i dynamics in D1R-EGFP and D2R-EGFP neurons in chronic mice

D1R EGFP miceD2R EGFP mice
ChronicAcuteamChronicAcuteam
S1S2S3mS1S2S3S4m
Cells (n)1013634613121547
t0 (min)6.10 ± 0.683.83 ± 0.851.90 ± 0.493.94 ± 2.10.59 ± 0.980.00 ± 0.560.28 ± 0.360.75 ± 0.70.40 ± 0.33
k2 (%/min)0.29 ± 0.010.32 ± 0.010.68 ± 0.030.43 ± 0.010.05 ± 0.05−0.071 ± 0.003−0.029 ± 0.004−0.12 ± 0.01−0.26 ± 0.01−0.12 ± 0.10−0.39 ± 0.15
k1 (%/min)0.27 ± 0.030.33 ± 0.030.72 ± 0.020.44 ± 0.020.77 ± 0.20−0.07 ± 0.01−0.03 ± 0.01−0.12 ± 0.02−0.25 ± 0.02−0.12 ± 0.09−0.40 ± 0.13
r = k2/k11.08 ± 0.140.967 ± 0.090.944 ± 0.060.999 ± 0.070.06 ± 0.231.08 ± 0.0131.07 ± 0.0471.00 ± 0.0251.04 ± 0.0121.04 ± 0.030.97 ± 0.26
  • t0, Delay of [Ca2+]i change to acute cocaine; m, animal number; n, number of selected neurons per mouse; k1, k2, slope Kp = Δ[Ca2+]it for phase 1 (p = 1, t0ttp) and phase 2 (p = 2, ttp).

  • aLuo, et al. (2011); m = animal numbers.