Table 1.

Clinical features in 145 patients tested in this study

VGKC-Ab ≥400 pM (n = 69)VGKC-Ab <400 pM (n = 76)
LE (n = 39)NMT/MoS (n = 19/2)Othersa (n = 9)LE (n = 20)NMT/MoS (n = 14/0)Othersa (n = 42)
Age, y (range)58 (6–82)52 (1–78)38 (1–70)48 (21–82)39 (21–85)41 (3–84)
Male: female ratio18:2115:64:58:127:726:16
Memory loss362316020
Confusion352418023
Seizuresb281412017
Neuromyotoniab22010145
MRI medial temporal high signal on T2 or FLAIRb31101305
Hyponatremiab2010506
Movement disordersc812107
Active tumorb1071015
Any dysautonomiad871164
VGKC-Ab titer, pM (range)895 (407–2493)780 (426–2593)561 (400–741)49 (0–384)93 (71–384)13 (0–386)
  • The data represent the number or median (range).

  • aFor a description of the patients in the Others category; see Materials and Methods.

  • bData were available for 144 patients.

  • cData were available for 124 patients.

  • dData available for 130 patients.