Overexpression phenotype of selected candidate genes assayed by axotomy
| Gene | Allele | Transgene | % Regeneration | na | p |
|---|---|---|---|---|---|
| oxIs12 | — | 70 | 105 | ||
| bcc-1 | basEx72 | Punc-47:bcc-1 | 12 | 83 | <0.0001 |
| cst-1 | basEx54 | Punc-47:cst-1 | 58 | 24 | 0.3456 |
| ldEx1050 | Pcst-1:cst-1 | 84 | 38 | 0.0898 | |
| dlk-1 | basEx4 | Punc-47:dlk-1 | 98 | 43 | <0.0001 |
| F16A11.2 | basEx40 | Punc-47:F16A11.2 | 17 | 48 | <0.0001 |
| fos-1 | syEx684 | Pfos-1:fos-1a/b:GFP | 82 | 88 | 0.0654 |
| basEx70 | Punc-47:fos-1 DN | 38 | 82 | <0.0001 | |
| gsk-3 | basEx6 | Punc-47:gsk-3 | 37 | 52 | 0.0001 |
| hsf-1 | basEx51 | Punc-47:hsf-1 | 60 | 52 | 0.2819 |
| muEx265 | Phsf-1:hsf-1 | 83 | 77 | 0.0783 | |
| ire-1 | basEx63 | Pdpy-30:ire-1 | 46 | 56 | 0.0063 |
| basEx61 | Prab-3:ire-1 | 49 | 86 | 0.0047 | |
| jnk-1 | lpIn2 | Pjnk-1:jnk-1 | 0 | 48 | <0.0001 |
| basEx21 | Punc-47:jnk-1 | 33 | 79 | <0.0001 | |
| basEx31 | Prab-3:jnk-1 | 13 | 61 | <0.0001 | |
| basEx23 | Pdpy-30:jnk-1 | 11 | 96 | <0.0001 | |
| basEx22 | Pdpy-30:jnk-1 (KK/AA) | 85 | 86 | 0.0161 | |
| basEx24 | Pdpy-30:jnk-1 (TY/AA) | 72 | 76 | 0.7419 | |
| kgb-2 | basEx20 | Punc-47:kgb-2 | 48 | 86 | 0.003 |
| basEx81 | Prab-3:kgb-2 | 54 | 85 | 0.035 | |
| basEx80 | Pdpy-30:kgb-2 | 22 | 80 | <0.0001 | |
| kin-18 | basEx25 | Punc-47:kin-18 | 70 | 77 | 1 |
| klf-1 | basEx65 | Punc-47:klf-1 | 32 | 121 | <0.0001 |
| mlk-1 | basEx30 | Punc-47:mlk-1 | 86 | 80 | 0.0084 |
| mtm-1 | basEx56 | Punc-47:mtm-1 | 33 | 123 | <0.0001 |
| sav-1 | Punc-47:sav-1 | 55 | 33 | 0.1479 | |
| sek-6 | basEx26 | Pdpy-30:sek-6 | 77 | 35 | 0.5175 |
| Psek-6:sek-6 DD | 80 | 45 | 0.2322 | ||
| sli-1 | basEx71 | Punc-47:sli-1 | 57 | 67 | 0.103 |
| smn-1 | basEx73 | Psmn-1:smn-1 | 14 | 85 | <0.0001 |
| tdp-1 | basEx75 | Punc-47:tdp-1 | 77 | 71 | 0.3014 |
| wts-1 | basEx28 | Pvha-6:wts-1 | 96 | 68 | <0.0001 |
| Prab-3:wts-1 | 99 | 72 | <0.0001 | ||
| Pdpy-30:wts-1 | 98 | 53 | <0.0001 | ||
| zbp-1 | basEx74 | Punc-47:zbp-1 | 24 | 78 | <0.0001 |
↵aNumber of axotomized axons.