Table 4.

Western blot quantification of Rictor fl/fl and cKO animal signaling proteins

	fl/fl %	Rictor spinal cord		Rictor corpus callosum
	fl/fl %	P14 (% control with p value)	P29 (% control with p value)	P14 (% control with p value)	P29 (% control with p value)
pAkt308/Akt	100	81.47 ± 10.51	107.85 ± 20.08	101.68 ± 19.21	92.42 ± 6.76
pAkt473/Akt	100	83.84 ± 11.24	88.80 ± 13.02	123.79 ± 9.57^*	67.40 ± 14.45^*
pERK/ERK	100	175.00 ± 82.73	101.68 ± 19.21	88.61 ± 27.33	150.39 ± 88.90
pS6RP/β-actin	100	25.46 ± 0.18^****	163.77 ± 22.98^*	24.56 ± 2.33^****	68.54 ± 4.48^**
pmTOR2448/mTOR	100	63.43 ± 1.3^****	83.56 ± 10.59	119.65 ± 12.71	60.95 ± 5.98^**
pmTOR2481/mTOR	100	42.19 ± 15.37^**	30.6 ± 6.65^****	97.01 ± 11.93	111.01 ± 16.08
Raptor/β-actin	100	56.57 ± 8.26^**	108.30 ± 8.09	74.41 ± 14.33	97.78 ± 4.48
Rictor/β-actin	100	0.90 ± 0.43^****	22.5 ± 5.71^****	37.32 ± 2.77^****	16.42 ± 4.31^****

Lysates prepared from P14 and P29 whole spinal cord lysates or white matter-enriched regions of the corpus callosum (see Results). Values ±SEM, n = 3,
↵*p ≤ 0.05,
↵**p ≤ 0.005,
***p ≤ 0.001,
↵****p ≤ 0.0001.