Table 1.

Ion channel gene expression in young and old mice^{^a}

Gene	Subunit	Old	Young	p
Scn1a	Nav1.1	2.21 ± 0.24 (5)	2.17 ± 0.28 (7)	0.91
Scn2a	Nav1.2	0.88 ± 0.29 (4)	0.84 ± 0.17 (7)	0.91
Scn5a	Nav1.5	0.15 ± 0.05 (4)	0.16 ± 0.03 (7)	0.96
Scn1b	NavΒ1	0.89 ± 0.17 (4)	0.89 ± 0.05 (7)	0.99
Scn2b	NavΒ2	1.23 ± 0.26 (4)	1.34 ± 0.13 (7)	0.69
Scn3b	NavΒ3	1.28 ± 0.18 (4)	1.24 ± 0.08 (7)	0.82
Hcn1	HCN1	2.12 ± 0.44 (4)	1.85 ± 0.36 (7)	0.65
Kcnn3	SK3	0.24 ± 0.05 (4)	0.24 ± 0.03 (7)	0.97
Cacna1c	Cav1.2	1.32 ± 0.33 (5)	0.96 ± 0.13 (7)	0.29
Cacna1d	Cav1.3	1.10 ± 0.22 (5)	0.78 ± 0.21 (7)	0.15

↵^aWe performed real-time qRT-PCR on substantia nigra samples taken from young and old mice. Values are mean ± SEM of the ratio of each gene's expression in relation to the control reference gene eEF1α1, with sample size in parentheses. p values were obtained from two-tailed, unpaired t tests.