Table 3.

Examples of genes differentially spliced in different cell types

GeneCoveragedIp valueFDR
AstrocytesFyn771−0.271.15 E-1761.95 E-174
Prom12510.861.12 E-1334.59 E-131
Ncam135760.241.63 E-1325.93 E-130
Ptprf480−0.581.03 E-1202.98 E-118
Srgap33080.691.99 E-841.44 E-82
Kif1a1800.753.12 E-661.76 E-64
Ptk2134−0.471.33 E-636.73 E-62
Cam2kg903−0.445.75 E-562.43 E-54
Mapk8270−0.556.98 E-372.36 E-35
Pkm21112−0.232.85 E-256.58 E-24
NeuronsAgrn907−0.5<1 E-300<1 E-300
App51810.2<1 E-300<1 E-300
Atp6v0a11815−0.66<1 E-300<1 E-300
Clta3032−0.81<1 E-300<1 E-300
Dync1i21618−0.82<1 E-300<1 E-300
Nfasc821−0.94<1 E-300<1 E-300
Rab630580.34<1 E-300<1 E-300
Mtss11244−0.65.19 E-2167.02 E-214
Srgap38340.621.69 E-1321.52 E-130
Lrp8328−0.753.23 E-1192.51 E-117
OligodendrocytesPhldb12947−0.58<1 E-300<1 E-300
Aplp213580.48<1 E-300<1 E-300
Capzb1350−0.585.97 E-2633.54 E-260
Add11515−0.511.41 E-2315.95 E-229
Mpzl111650.454.37 E-2273.15 E-223
Cldnd11187−0.62.49 E-2098.2 E-207
Enpp215500.231.63 E-2092.35 E-191
H2afy3200.431.31 E-355.11 E-34
Mtss11810.441.58 E-244.54 E-23
Snap251000.398.8 E-222.1 E-20
MicrogliaClstn15880.91<1 E-300<1 E-300
H1312630.26.2 E-2963.94 E-283
Sena4d7680.61.19 E-2826.79 E-280
App705−0.65.33 E-2402.04 E-237
Add15090.579.97 E-1883.17 E-185
Lass54080.652.49 E-1747.12 E-172
Rapgef13550.452.22 E-1735.79 E-171
Fmnl14930.441.32 E-1583.15 E-156
Fez28530.361.61 E-1393.08 E-137
Fyn1310.687.07 E-899.31 E-87
EndothelialAdam158930.7<1 E-300<1 E-300
Mcf2l6290.74<1 E-300<1 E-300
Palm942−0.65<1 E-300<1 E-300
Ablim110250.47<1 E-300<1 E-300
Mprip3292−0.51<1 E-300<1 E-300
Actn41805−0.31<1 E-300<1 E-300
Ktn1809−0.73.84 E-2261.02 E-223
Arhgef18650.362.23 E-2195.66 E-217
Eif4 h11990.461.14 E-1972.29 E-195
Pkp45770.631.68 E-1953.26 E-193
  • The coverage, delta inclusion (dI), p value, and false discovery rate (FDR) are listed. To obtain dI values, we first calculated the ratio of inclusion junction tags to inclusion plus skipping junction tags in each cell type and then determined the differences of the ratios between cell types. dI essentially quantifies the magnitude of the difference between the splicing of the two groups being compared (1 or −1 represents maximum difference, whereas 0 represents no difference).