Table 1.

Baseline activity of animals used in the study

Bar test (immobility time in seconds)Drag test (number of steps)Rotarod test (time on rod in seconds)
6-OHDA rats (n = 32)479 ± 31**
    Ipsilateral16.8 ± 1.711.4 ± 0.2
    Contralateral30.8 ± 2.6*2.5 ± 0.2*
Naive ratsa1.2 ± 0.111.8 ± 0.21138 ± 61
MPTP-treated mice (n = 27)11.6 ± 2.1**11.1 ± 0.3**589 ± 25**
Naive mice (n = 8)0.5 ± 0.114.1 ± 0.5850 ± 22
Naive NOP+/+ mice (n = 14)nt13.9 ± 0.6nt
Naive NOP−/− mice (n = 12)nt17.1 ± 0.6**nt
  • The number of animals used to generate the data is indicated in parentheses. Data have been analysed using the Student's t test for unpaired data.

  • *p < 0.01, different from the ipsilateral side;

  • **p < 0.01, different from naive control animals. nt, Not tested.

  • aTaken from Marti et al. (2008).