Bar test (immobility time in seconds) | Drag test (number of steps) | Rotarod test (time on rod in seconds) | |
---|---|---|---|
6-OHDA rats (n = 32) | 479 ± 31** | ||
Ipsilateral | 16.8 ± 1.7 | 11.4 ± 0.2 | |
Contralateral | 30.8 ± 2.6* | 2.5 ± 0.2* | |
Naive ratsa | 1.2 ± 0.1 | 11.8 ± 0.2 | 1138 ± 61 |
MPTP-treated mice (n = 27) | 11.6 ± 2.1** | 11.1 ± 0.3** | 589 ± 25** |
Naive mice (n = 8) | 0.5 ± 0.1 | 14.1 ± 0.5 | 850 ± 22 |
Naive NOP+/+ mice (n = 14) | nt | 13.9 ± 0.6 | nt |
Naive NOP−/− mice (n = 12) | nt | 17.1 ± 0.6** | nt |