Sleep during the 210 min stimulation period and the whole night
| Parameter | Study I | Study II | ||||
|---|---|---|---|---|---|---|
| Driving | Sham | P value | Driving | 2-Click | P value | |
| 210 in stimulation interval | ||||||
| W (%) | 1.3 ± 0.6 | 2.0 ± 1.1 | 0.620 | 2.3 ± 0.9 | 1.1 ± 0.9 | 0.288 |
| S1 (%) | 4.2 ± 1.7 | 3.8 ± 1.0 | 0.874 | 5.8 ± 0.8 | 5.0 ± 0.6 | 0.309 |
| S2 (%) | 57.2 ± 3.5 | 57.8 ± 3.6 | 0.779 | 50.2 ± 2.1 | 51.8 ± 2.4 | 0.540 |
| SWS (%) | 27.5 ± 3.8 | 27.7 ± 3.1 | 0.960 | 28.5 ± 2.3 | 31.0 ± 2.7 | 0.369 |
| REM (%) | 9.8 ± 2.8 | 8.7 ± 1.5 | 0.666 | 13.2 ± 1.7 | 11.1 ± 1.2 | 0.312 |
| Whole night | ||||||
| TST (min) | 410.0 ± 6.1 | 421.7 ± 4.4 | 0.100 | 417.8 ± 3.9 | 422.7 ± 2.5 | 0.284 |
| W (%) | 2.1 ± 0.7 | 4.2 ± 1.9 | 0.218 | 5.4 ± 1.9 | 2.8 ± 1.3 | 0.103 |
| S1 (%) | 6.1 ± 1.0 | 5.4 ± 0.5 | 0.606 | 6.2 ± 0.7 | 5.8 ± 0.9 | 0.725 |
| S2 (%) | 57.6 ± 1.8 | 56.3 ± 2.1 | 0.458 | 50.1 ± 2.0 | 53.0 ± 1.8 | 0.210 |
| SWS (%) | 16.2 ± 1.4 | 16.6 ± 1.4 | 0.725 | 21.6 ± 1.0 | 21.2 ± 1.8 | 0.820 |
| REM (%) | 17.9 ± 1.3 | 17.5 ± 1.2 | 0.796 | 16.7 ± 1.6 | 17.2 ± 1.2 | 0.737 |
Mean (±SEM) percentage of time spent in different sleep stages during the 210 min stimulation period and 7 h nocturnal sleep interval for Study I (Driving stimulation vs Sham) and Study II (Driving stimulation vs 2-Click stimulation). There were no significant differences between conditions. TST, total sleep time (in minutes); W, wake; S1, stage 1 sleep; S2, stage 2 sleep.