Table 1.

Passive and active membrane properties of BLA pyramidal cells

Group housedSocially isolatedFp
Baseline1-EBIOApaminBaseline1-EBIOApamin
Vm (mV)−67.65 ± 0.77−67.07 ± 1.22−67.18 ± 1.07−66.71 ± 0.91−66.73 ± 1.17−65.9 ± 1.620.2690.9288
Rin (MΩ)166.6 ± 16.78145.6 ± 10.17129.3 ± 12.94183.3 ± 22.61147.0 ± 15.72156.5 ± 22.591.2430.2985
Rheobase (pA)210.9 ± 17.12212.1 ± 23.37182.6 ± 21.18190 ± 16.21185.6 ± 25.08154.7 ± 27.110.6950.629
Ih (mV)−4.98 ± 0.92−3.91 ± 0.81−4.71 ± 1.82−4.47 ± 0.42−5.52 ± 0.46−4.86 ± 0.750.61540.6886
AP peak (mV)78.59 ± 3.0478.53 ± 3.0674.42 ± 3.9683.60 ± 1.6585.96 ± 1.9680.65 ± 3.501.8840.1078
AP threshold (mV)−44.95 ± 1.85−43.41 ± 1.72−43.42 ± 2.4−47.31 ± 1.80−44.43 ± 2.82−47.07 ± 1.580.77910.5682
  • Shown is a summary of the effect of adolescent social isolation and SK channel modulators on other passive and active membrane properties of BLA pyramidal neurons. AP, Action potential.