Body weight | Body weight in grams | ↓ | ↓ | ̶ |
Open field | Time in center/time in periphery | ̶ | ̶ | ̶ |
Distance traveled | ↓ | ↓ | ̶ |
Velocity | ↓ | ↓ | ̶ |
Dark/light | Time spent in dark chamber | ↑ | ̶ | ̶ |
Time spent in light chamber | ↓ | ̶ | ̶ |
Latency to enter light chamber | ↑ | ↑ | ̶ |
Distance traveled | ↓ | ↓ | ̶ |
Elevated plus maze | Time in open arms/both arms | ̶ | ̶ | ̶ |
Distance traveled | ̶ | ↓ | ̶ |
Velocity | ̶ | ↓ | ̶ |
Morris water maze | Training: latency to platform | ↑ | ↑ | ̶ |
Training: distance traveled | ↑ | ↑ | ̶ |
Training: thigmotaxis | ↑ | ̶ | ̶ |
Training: velocity | ̶ | ↑ | ↑ |
Probe: % time in target quadrant | ↓ | ̶ | ̶ |
Probe: frequency of target platform location crossing | ̶ | ̶ | ̶ |
Probe: thigmotaxis | ↑ | ̶ | ̶ |
Probe: velocity | ̶ | ̶ | ̶ |
Nesting | Nest width | ↓ | ↓ | ̶ |
Nest height | ↓ | ↓ | ̶ |
Three choice social interaction test | Front versus back target | ̶ | ̶ | ̶ |
Social versus inanimate target | ̶ | ̶ | ̶ |
Familiar versus novel target | ↓ | ̶ | ̶ |
Locomotor test | 2 h | ̶ | ̶ | ̶ |
First 5 min | ↓ | ↓ | ̶ |
Rotarod | Motor learning | ̶ | ↓ | ̶ |
Motor coordination | ↓ | ↓ | ̶ |
Marble burying | No. of buried marbles | ↓ | ↓ | ̶ |
Grooming | Time spent grooming | ̶ | ̶ | ̶ |
No. of bouts | ̶ | ̶ | ̶ |
Time per bout | ̶ | ̶ | ̶ |
Electrophysiology | | | | |
| I/O curves | ↓ | ↓ | ↓ |
| PPR | ̶ | ̶ | ̶ |
| LTP | ↓ | ̶ | ̶ |
| mGluR-LTD | ̶ | ↓ | ̶ |
| mEPSC amplitude | ̶ | ̶ | ̶ |
| mEPSC frequency | ↓ | ↓ | ̶ |
| NMDA/AMPA | ↓ | ↓ | ̶ |